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Question:

MIL gave dog grape flavored Benadryl is he gonna be ok?

I'm honestly a bit freaked out right now and could really use some advice. My mother-in-law was babysitting our 3-year-old golden retriever, Max, while we were out of town this weekend. Bless her heart, she was trying to help with his allergies and ended up giving him grape-flavored Benadryl instead of the regular one. I know grapes are a big no-no for dogs, and now I'm worried sick. He's been behaving a bit off—kind of sluggish and not his usual bouncy self. He's drinking water but hasn't shown much interest in food since we got back last night. Has anyone else had this happen? Should I rush him to the vet, or is there something I can do at home to help him feel better? Any advice would be so appreciated. Thank you!!

Answer:

Hello there, thanks for reaching out. It’s understandable to be concerned after realizing what your dog has ingested. Benadryl in itself is typically safe for dogs in the correct dosages and plain formulations, but there are a couple of important considerations here.

First, the grape flavoring is a worry because grapes (and raisins) can be toxic to dogs. They can cause kidney failure, even in small amounts for some pets. We don't know exactly how much grape extract is in the flavored Benadryl, but it could pose a risk.

The second concern is about the dosage and concentration. Make sure to check the Benadryl's packaging for the active ingredient diphenhydramine's concentration, as human formulations might differ significantly from what is safe for dogs.

At home, keep an eye on your dog for any signs of distress. Watch for vomiting, diarrhea, lethargy, excessive drooling, or decreased appetite and urination, as these might hint at a problem. If any of these symptoms appear, or if your dog seems unwell or unusual in any way, it’s crucial to seek veterinary attention immediately.

To ensure your pet's safety and health, consider scheduling a video consult with us at Dial A Vet. We can offer further guidance and peace of mind. Take care and give your furry friend a little extra love today!

Answered by

Louise - Senior Veterinary Nurse, Dial A Vet

June 17, 2025

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The "Ask a Vet" forum on Dial A Vet offers general information and helpful tips on pet health, but it's not a substitute for professional veterinary care. The advice here doesn't create a veterinarian-client-patient relationship, and our vets can't diagnose or treat your pet remotely. For emergencies or specific medical concerns, always contact your local veterinarian immediately. Your pet's health is unique, and decisions should only be made after consulting with a qualified professional. By using this forum, you acknowledge these limitations and agree to seek in-person veterinary advice for all your pet's health needs. View our content guidelines.
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