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Question:

M/15 stage 3 kidney disease cat won't eat even w/Miritaz

I’m really at a loss and could use some advice. My 15-year-old cat has recently been diagnosed with stage 3 kidney disease, and it's been a tough journey. We’ve been trying to manage his symptoms and make him comfortable, but now he’s refusing to eat, even though we’ve started giving him Mirtazapine (Miritaz) to stimulate his appetite. His once-healthy weight is dropping quickly, and it breaks my heart to see him so disinterested in his favorite foods. We've tried everything from warming up his meals to offering him a variety of wet and dry options, but nothing seems to entice him. Has anyone else dealt with a similar situation? I’m desperate for any tips or tricks that might help him start eating again. Thank you in advance for your support.

Answer:

Hello there! I'm sorry to hear that your cat isn't eating, especially with a condition as delicate as stage 3 kidney disease. It's understandable to be concerned when your feline friend turns down food. Reduced appetite can be common in cats with kidney disease due to nausea or even the general feeling of being unwell.

Mirtazapine (often branded as Miritaz) typically helps with appetite, so if it’s not working, there might be something deeper going on. It could be related to the progression of the kidney disease, but it's also possible that your cat is dealing with other issues like an upset stomach, dental problems, or even stress.

At home, offering smaller, more frequent meals can sometimes help, and trying different textures or temperatures of food might entice him to eat. Sometimes, warming food slightly enhances its smell and can stimulate appetite. Ensure he has access to fresh water at all times and monitor him closely.

Watch for signs such as vomiting, diarrhea, lethargy, or rapid weight loss, as these could indicate a more serious issue requiring immediate attention.

I recommend scheduling a video consult with one of our Dial A Vet professionals as soon as possible. They can guide you through this and help get your kitty back on track.

Answered by

Louise - Senior Veterinary Nurse, Dial A Vet

June 18, 2025

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The "Ask a Vet" forum on Dial A Vet offers general information and helpful tips on pet health, but it's not a substitute for professional veterinary care. The advice here doesn't create a veterinarian-client-patient relationship, and our vets can't diagnose or treat your pet remotely. For emergencies or specific medical concerns, always contact your local veterinarian immediately. Your pet's health is unique, and decisions should only be made after consulting with a qualified professional. By using this forum, you acknowledge these limitations and agree to seek in-person veterinary advice for all your pet's health needs. View our content guidelines.
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