Is it normal for my puppy to be lethargic and not eat much after shots from Wednesday afternoon?

Since Wednesday afternoon, after my puppy got her shots, she seems really lethargic and hasn’t been eating much. I know that vaccinations can sometimes cause mild side effects, but I'm concerned because she's usually so energetic and playful. Is this normal behavior after getting vaccinated, or should I bring her back to the vet to get checked out?

Answer

It’s not uncommon for puppies to experience lethargy and a decrease in appetite after vaccinations. While mild side effects are normal, continued symptoms should be monitored closely.

  • Monitor your puppy's symptoms over the next 24–48 hours
  • Ensure she stays hydrated—encourage water intake
  • Consider a follow-up with the vet if no improvement is seen

Vaccinations can sometimes make puppies feel a little under the weather as their immune system is responding to the vaccine. Common side effects include tiredness and loss of appetite, which typically resolve in a day or two. However, if your puppy is extremely lethargic, not drinking water, or if her condition worsens, it’s important to consult your veterinarian for further advice.

Book a consultation with a licensed vet at Dial A Vet for just $49 AUD if you're unsure or symptoms are getting worse.

Frequently Asked Questions

  • What are common side effects of vaccinations in puppies?

    Common side effects can include mild lethargy, a slight decrease in appetite, mild fever, and soreness at the injection site. These usually subside within 24–48 hours.

  • When should I be concerned about my puppy's symptoms post-vaccination?

    If the lethargy persists for more than two days, or if your puppy is vomiting, having diarrhea, or has a significant loss of appetite or energy, it is advisable to contact your vet.

  • How can I help my puppy recover after vaccinations?

    Ensure she has a quiet and comfortable place to rest, provide plenty of fresh water, and offer a small, bland meal if she’s willing to eat.

If this is an emergency, please seek immediate veterinary care.

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