Can von willebrand disease iii be prevented through breeding?

Von Willebrand disease III primarily affects Scottish Terriers. The condition is autosomal recessive, caused by a mutation in the VWF gene. DNA testing for the VWF gene is available and gives a definitive answer. Affected dogs need two copies of the mutation. Carriers (one copy) are clinically normal. Never breed two carriers — Carrier × Clear pairings produce no affected puppies. Responsible breeders test both parents before any mating. Our vets can help with breeding guidance or pre-purchase advice for at-risk breeds.