Which dog breeds are at risk for von willebrand disease iii and can it be prevented?

Von Willebrand disease III primarily affects Nederlandse Kooikerhondjes. The condition is autosomal recessive, caused by a mutation in the VWF gene. DNA testing for the VWF gene is available and gives a definitive answer. Affected dogs need two copies of the mutation. Carriers (one copy) are clinically normal. Never breed two carriers — Carrier × Clear pairings produce no affected puppies. Responsible breeders test both parents before any mating. Not sure how to interpret your breeder's health testing? Our vets can break it down for you in a quick consult.