Can NCL5 be cured?
Reviewed by Dial A Vet Team
Category
Muscle/Neurological
Traits
Neuronal Ceroid Lipofuscinosis 5
Question Number
Q3
Pet Owner Description
Is there any treatment for NCL5 or any research that gives hope?
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Answer
NCL5 has no cure and no treatment that slows progression. Research into gene therapy for NCL variants is active in both human and veterinary medicine, but nothing clinically available yet. Treatment is symptomatic: seizure control, supportive care, and comfort. The disease is always progressive and fatal, typically within 1–2 years of symptom onset. Prevention through DNA testing of CLN5 in breeding stock is the most impactful thing we can do right now.
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