Globoid Cell Leukodystrophy (Irish Setter) in dogs
Immune/AutoimmuneGloboid Cell Leukodystrophy (Irish Setter)

How do I tell if my dog has globoid cell leukodystrophy?

Reviewed by Dial A Vet Team

Category

Immune/Autoimmune

Traits

Globoid Cell Leukodystrophy (Irish Setter)

Question Number

Q1

Pet Owner Description

I noticed some changes in my Irish Setter and a friend mentioned globoid cell leukodystrophy. How would I know if that's what's going on?

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Answer

Signs of the disease usually appear between 1 and 5 months of age. Affected puppies show uncoordinated movements, tremors, and loss of normal muscle reflexes. As the condition progresses, blindness and paralysis develop. The GALC gene mutation responsible for this condition can be identified with a DNA test. Schedule a vet visit to get a clear picture. Our vets are also available for a consult if you want guidance before the appointment.

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