
How do I tell if my dog has globoid cell leukodystrophy?
Reviewed by Dial A Vet Team
Category
Immune/Autoimmune
Traits
Globoid Cell Leukodystrophy (Irish Setter)
Question Number
Q1
Pet Owner Description
I noticed some changes in my Irish Setter and a friend mentioned globoid cell leukodystrophy. How would I know if that's what's going on?

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Answer
Signs of the disease usually appear between 1 and 5 months of age. Affected puppies show uncoordinated movements, tremors, and loss of normal muscle reflexes. As the condition progresses, blindness and paralysis develop. The GALC gene mutation responsible for this condition can be identified with a DNA test. Schedule a vet visit to get a clear picture. Our vets are also available for a consult if you want guidance before the appointment.
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