Which dog breeds are at risk for fetal onset neuroaxonal dystrophy and can it be prevented?

Fetal Onset Neuroaxonal Dystrophy has been identified in Giant Schnauzers and Beagles. The condition is autosomal recessive, caused by a mutation in the MFN2 gene. DNA testing for the MFN2 gene is available and gives a definitive answer. Affected dogs need two copies of the mutation. Carriers (one copy) are clinically normal. Never breed two carriers — Carrier × Clear pairings produce no affected puppies. Ask your breeder for DNA test results on both parents before committing to a puppy. Not sure how to interpret your breeder's health testing? Our vets can break it down for you in a quick consult.