
What should I do if my Malamute has been diagnosed with polyneuropathy?
Reviewed by Dial A Vet Team
Category
Muscle/Neurological
Traits
Early-Onset Progressive Polyneuropathy (Alaskan Malamute)
Question Number
Q2
Pet Owner Description
Our Malamute tested positive for AMPN and is showing symptoms. There doesn't seem to be a treatment. What can we actually do?

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Answer
I'm really sorry — AMPN is a hard diagnosis because there's no cure. Focus on quality of life: maintain lean body condition, use supportive harnesses with handles, ramps instead of stairs, and non-slip flooring. Swimming can help maintain muscle mass without strain. Protect paws with booties if he's dragging them. Watch for urinary incontinence or swallowing difficulties as the disease progresses. Most affected dogs are eventually euthanized due to mobility loss — having honest conversations about quality-of-life benchmarks early helps. Please inform the breeder so future pairings can be planned responsibly. Our vets can support you through management and the harder decisions.
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