Can cystinuria be prevented through breeding (Miniature Pinscher)?
Reviewed by Dial A Vet Team
Category
Metabolic/Digestive
Traits
Cystinuria (Miniature Pinscher)
Question Number
Q5
Pet Owner Description
We're looking at getting a Miniature Pinscher and I've read about cystinuria. What should I ask the breeder?
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Answer
Cystinuria primarily affects Miniature Pinschers. The condition is dominant, caused by a mutation in the SLC7A9 gene. DNA testing for the SLC7A9 gene is available and gives a definitive answer. A single copy of the mutation can cause disease. Affected dogs and known carriers should be carefully managed in breeding programs. Responsible breeders test both parents before any mating. Our vets can help with breeding guidance or pre-purchase advice for at-risk breeds.
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