
What breeds are most prone to cerebellar cortical degeneration?
Reviewed by Dial A Vet Team
Category
Muscle/Neurological
Traits
Cerebellar Cortical Degeneration
Question Number
Q5
Pet Owner Description
I want to understand which breeds are most affected by cerebellar cortical degeneration and whether there's a way to screen for it before getting a puppy.

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Answer
Cerebellar Cortical Degeneration primarily affects Vizslas. The condition is autosomal recessive, caused by a mutation in the SNX14 gene. DNA testing for the SNX14 gene is available and gives a definitive answer. Affected dogs need two copies of the mutation. Carriers (one copy) are clinically normal. Never breed two carriers — Carrier × Clear pairings produce no affected puppies. Test all breeding stock and share results with your breed club. Not sure how to interpret your breeder's health testing? Our vets can break it down for you in a quick consult.
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