Can canine multifocal retinopathy 2 be prevented through breeding?

Canine Multifocal Retinopathy 2 primarily affects Coton De Tulears. The condition is autosomal recessive, caused by a mutation in the BEST1 gene. DNA testing for the BEST1 gene is available and gives a definitive answer. Affected dogs need two copies of the mutation. Carriers (one copy) are clinically normal. Never breed two carriers — Carrier × Clear pairings produce no affected puppies. Responsible breeders test both parents before any mating. Not sure how to interpret your breeder's health testing? Our vets can break it down for you in a quick consult.