Dog unexpectedly died, shortly after taking Prednisone and Amoxicillin - why?

I'm really sorry to hear about your loss. Losing a pet is incredibly difficult, and it's important to understand what might have happened. Prednisone is a steroid that helps with inflammation, and Amoxicillin is an antibiotic used to fight infections. While both are commonly prescribed and generally safe when used properly, there can be rare adverse reactions or complications.



One possibility is an allergic reaction, which can sometimes be severe and cause issues like difficulty breathing or collapse. Prednisone can also affect the heart and immune system, potentially leading to complications, especially if the underlying condition was severe. In some cases, interactions between medications or an undiagnosed health issue can contribute to such a sudden event.



At this point, a conclusive answer would typically require a veterinarian’s examination or a post-mortem analysis. However, reflecting on any symptoms your dog might have shown before passing—like lethargy, vomiting, or difficulty breathing—could provide clues.



Going forward, if you notice signs like vomiting, diarrhea, excessive drinking, or changes in behavior when your pets are on medication, these are good reasons to check in with a veterinarian immediately.



If you're feeling uncertain or have concerns about other pets or medications, consider booking a video consult with us at Dial A Vet. We're here to support you during this time.