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Question:

Cat with High ALT/AST and A-amylase.

I'm reaching out because I'm really worried about my fur baby, Mittens. We just got back from the vet, and they told us her blood work showed high ALT/AST and A-amylase levels. I'm honestly freaking out a bit because I know these are liver and pancreas indicators, but I don't fully understand what it means for her health. Mittens has been acting a little off lately, more lethargic than usual and not very interested in her food. She's always been a playful and voracious eater, so this is totally unlike her. Has anyone dealt with something similar? The vet mentioned possibilities like liver issues or pancreatitis, which scares me. We’re doing further tests, but any advice or similar experiences would help. She's my little shadow, and I just want to make sure I'm doing everything I can to help her feel better. Thanks so much in advance for any guidance or support!

Answer:

Hello! I'm so glad you reached out about your cat's elevated ALT/AST and amylase levels. While these numbers can be a bit concerning, they give us clues about how your cat's liver and pancreas might be functioning.



Elevated ALT (alanine aminotransferase) and AST (aspartate aminotransferase) levels often point to liver stress or damage. This could be due to various reasons like inflammation, infection, toxins, or even a reaction to medication. Elevated amylase, on the other hand, typically involves the pancreas and might suggest an issue like pancreatitis.



In terms of at-home care, make sure your cat has a calm environment with easy access to fresh water and high-quality, easily digestible food. Observe their behavior closely—look for signs like vomiting, lethargy, changes in appetite, or jaundice (a yellow tint to the skin or eyes).



If you notice any of these symptoms, or if your cat seems unwell, it's important to seek veterinary care promptly. These can be signs of a more serious problem that needs professional attention.



I'd recommend booking a video consult with one of our vets at Dial A Vet to discuss these lab results in more detail and plan the best course of action for your cat’s health. We're here to help you navigate this!

Answered by

Louise - Senior Veterinary Nurse, Dial A Vet

June 19, 2025

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The "Ask a Vet" forum on Dial A Vet offers general information and helpful tips on pet health, but it's not a substitute for professional veterinary care. The advice here doesn't create a veterinarian-client-patient relationship, and our vets can't diagnose or treat your pet remotely. For emergencies or specific medical concerns, always contact your local veterinarian immediately. Your pet's health is unique, and decisions should only be made after consulting with a qualified professional. By using this forum, you acknowledge these limitations and agree to seek in-person veterinary advice for all your pet's health needs. View our content guidelines.
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