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Question:

Carboplatin (and other chemotherapy) potential for liver / kidney complications

I’m really hoping some of you can help with some advice or shared experiences. My 9-year-old cat, Shadow, was recently diagnosed with cancer, and the vet has recommended starting chemo with carboplatin. I’m just really worried because I’ve been reading up on the side effects, and it seems like there could be some serious risks, especially concerning the liver and kidneys. Shadow’s always been a bit on the sensitive side health-wise, and the last thing I want is to make things worse for her. Has anyone else gone through chemo with their pets, especially with this kind of treatment? Any insights into how it affected their liver or kidney health would be so appreciated. I just want to make the best decision for her without adding to her pain. Thanks in advance for any help you can give.

Answer:

Hello there! It's great that you're staying informed about your pet's health and treatment options. Carboplatin, along with other chemotherapy drugs, can indeed have effects on the liver and kidneys. These organs help process and eliminate toxins from the body, so when they're exposed to certain drugs, some degree of strain or damage is possible.



Chemotherapy can potentially lead to issues such as liver enzyme elevation or reduced kidney filtration efficiency. However, the risk varies depending on the individual pet's overall health, the dosage, and the treatment duration. It's important to monitor your pet closely during chemotherapy.



At home, keeping your pet hydrated is key. Ensure they always have access to fresh water, as hydration supports kidney function. Providing a balanced diet, perhaps with input from your vet, can also be beneficial.



Watch for signs like decreased appetite, vomiting, lethargy, increased thirst, or changes in urination. These could indicate complications needing immediate attention.



If your pet shows any concerning symptoms or you have further questions about their treatment plan, booking a video consult with one of our vets on Dial A Vet can provide you with personalized guidance. We're here to help you through every step of your pet's care journey.

Answered by

Louise - Senior Veterinary Nurse, Dial A Vet

June 21, 2025

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The "Ask a Vet" forum on Dial A Vet offers general information and helpful tips on pet health, but it's not a substitute for professional veterinary care. The advice here doesn't create a veterinarian-client-patient relationship, and our vets can't diagnose or treat your pet remotely. For emergencies or specific medical concerns, always contact your local veterinarian immediately. Your pet's health is unique, and decisions should only be made after consulting with a qualified professional. By using this forum, you acknowledge these limitations and agree to seek in-person veterinary advice for all your pet's health needs. View our content guidelines.
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